To me, Calvin & Hobbes is a wonderful example of taking one art form (comics) and exploring every way to reach the epitome of its elements (writing, art, and humor). For example, Bill Watterson captured the movement of his characters in a way that we can easily imagine through simple static drawings.
Animator Adam Brown was able to use the original Watterson drawings as keyframes for this 30-second animation. What a labor of love. Imagine investing Mr. Watterson and Mr. Brown’s passion into your art, whatever that might be.
The Elements of Simple 